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Pengabdian Masyarakat 2021

PENGOBATAN MASSAL SKABIES DI PANTI ASUHAN/PONDOK PESANTREN ASYSYAFI’IYAH KEMIRIKEBO, TURI, SLEMAN

Abstrak

Scabies merupakan penyakit kulit yang disebabkan oleh parasit Sarcoptes scabiei var hominis. Disebut juga dengan kudis dan identik dengan lingkungan yang padat dan kotor. Skabies sangat identik dengan penyakit di pesantren. Panti asuhan/pondok pesantren Asysyafi’iyah, Kemirikebo, Turi, Sleman tercatat memiliki sebanyak 80 santri. Dari hasil pemeriksaan sebanyak 40 santri mengalami skabies, 20 orang diantaranya juga mengalami komplikasi berupa infeksi sekunder. Telah diberikan pengobatan antiskabies menggunakan tablet ivermectin dan krim Scabimite®. Pada kegiatan ini juga dilakukan penyuluhan mengenai skabies dan pola hidup bersih dan sehat (PHBS). Diharapkan dari kegiatan ini, penularan skabies di PA/PP Asysyafi’iyah dapat dikontrol dan penularan lebih lanjut dapat dicegah.

Pemakalah Forum Ilmiah 2021

Correlation between Lipid Profile and Disease Severity in Psoriasis Patients of Dr. Sudirman Kebumen District Hospital Central Java Indonesia

Abstrak

ABSTRACT Psoriasis is a chronic inflammatory disease characterized by skin inflammation, epidermal hyperplasia, increased risk of arthritis, cardiovascular morbidity, and psychosocial challenges. Previous studies revealed the association of psoriasis with cardiometabolic diseases, in which dyslipidemia is a common feature. The objective of the study is to identify the correlation between lipid profile and disease severity in psoriasis patients. This study employed a cross-sectional design by using primary data from patients visiting the outpatient department of Dr Soedirman Kebumen District Hospital, Central Java. Disease severity was examined using Psoriasis Area and Severity Index (PASI) score. The levels of triglyceride, HDL- and LDL- cholesterol, and total cholesterol were measured from fasting blood plasma on the same day. Data were compared by utilizing one-way ANOVA or Kruskal-Wallis test as appropriate, and correlation between lipid levels and PASI score was analyzed by utilizing the Spearman correlation test. There were 33 psoriasis patients (20 male and 13 female) enrolled in this study; mean age was 43,6 ± 16,7 years old, and mean disease duration was 8,2 ± 9,5 years. Disease severity was mild in 19 (57,5%), moderate in 5 (15,2%), and severe in 9 (27,3%) patients, and mean PASI score was 12,8 ± 10,1. There were no significant differences of triglyceride levels (p=0,700), HDL-cholesterol levels (p=0,743), LDL-cholesterol levels (p=0,840), and total cholesterol (p=0,890) among groups of disease severity. There was no significant correlation between PASI score and triglyceride (r=0,028; p=0,879), HDL-cholesterol (r=-0,052; p= 0,775, LDL-cholesterol (r=-0,043; p=0,812) and total cholesterol levels (r=-0,028; p=0,875). However, there was a significant correlation between PASI score and disease duration (r=0,423; p=0,014). Meanwhile, there was no significant correlation between disease severity and lipid profile in psoriasis patients.

Penelitian 2019

Hubungan Derajat Keparahan Psoriasis dan Profil Lipid Plasma pada Pasien Psoriasis di RSUD Kebumen

Abstrak

Latar Belakang: Psoriasis adalah penyakit inflamasi kronis yang ditandai dengan peradangan kulit, hiperplasia epidermis, peningkatan risiko arthritis, morbiditas kardiovaskular, dan masalah psikososial. Penelitian sebelumnya melaporkan adanya hubungan psoriasis dengan penyakit kardiometabolik, dengan dislipidemia sebagai salah satu gambaran klinis utama. Tujuan: Penelitian ini bertujuan untuk memahami korelasi antara profil lipid dan tingkat keparahan penyakit pada pasien psoriasis. Metode: Penelitian ini menggunakan desain cross-sectional dengan menggunakan data primer dari pasien yang berkunjung ke poliklinik kulit dan kelamin RSUD dr Soedirman Kabupaten Kebumen, Jawa Tengah. Tingkat keparahan penyakit diukur dengan menggunakan psoriasis area and severity index (PASI), sedangkan kadar trigliserida, HDL dan LDL-kolesterol, dan kolesterol total, diukur dari plasma darah puasa pada hari yang sama. Data dianalisis menggunakan uji oneway ANOVA atau Kruskal-Wallis, dan korelasi antara tingkat lipid dan skor PASI dianalisis menggunakan tes korelasi Spearman. Hasil: Terdapat 33 pasien psoriasis (20 laki-laki dan 13 perempuan) yang terdaftar dalam penelitian ini, rata-rata usia adalah 43,6 ± 16,7 tahun dan durasi penyakit rata-rata adalah 8,2 ± 9,5 tahun. Tingkat keparahan penyakit ringan pada 19 (57,5%), sedang di 5 (15,2%), dan berat pada 9 (27,3%) pasien, dan skor rata-rata PASI adalah 12,8 ± 10,1. Tidak ada perbedaan yang signifikan dari kadar trigliserida (p=0.700), kadar HDL-kolesterol (p= 0.743), kadar LDL-kolesterol (p=0.840), dan kolesterol total (p=0.890) di antara kelompok keparahan penyakit. Tidak ada korelasi yang signifikan antara skor PASI dan trigliserida (r=0.028; p=0.879), HDL-kolesterol (r=-0,052; p=0.775), LDL-kolesterol (r=-0.043; p=0,812) dan kadar kolesterol total (r=-0,028; p=0,875). Namun, terdapat korelasi moderat yang signifikan antara skor PASI dan durasi penyakit (r= 0.423; p=0,014). Kesimpulan: Tidak ada korelasi yang signifikan antara keparahan penyakit dan profil lipid pada pasien psoriasis.

Publikasi 2012

Visual pathway morphometry in visual field defects

Abstrak

Het gezichtsvermogen is een cruciale sensorische functie voor de mens. Mensen hebben een gezichtsveld dat van boven naar beneden en van links naar rechts bijna een gebied van 180 graden omvat. Hierdoor zijn zij zich constant bewust van hun omgeving. Het centrale deel van het gezichtsveld, de fovea of macula, wordt gebruikt voor nauwkeurige visuele taken zoals lezen, het waarnemen van details van een object of het herkennen van kleuren. De rest van het gezichtsveld, ook wel het perifere gezichtsveld genoemd, geeft ons overzicht en stelt ons in staat om beweging waar te nemen. Het stelt ons ook in staat om nog wat zien wanneer er weinig licht is. ! Het netvlies is een laag met zenuwcellen aan de achterkant van het oog. Het netvlies vangt het licht op dat binnenvalt in het oog en zet dit om in een neuraal signaal. Net als andere lichaamsfuncties kan het netvlies, en daarmee het gezichtsveld, worden aangetast door ziektes. Het centrale gezichtsveld kan aangetast worden door maculadegeneratie, waarbij de zenuwcellen in het centrale deel van het netvlies beschadigd worden. Bij de oogziekte glaucoom wordt vooral het perifere deel van het netvlies aangetast. Met behulp van MRI (magnetic resonance imaging) hebben we beelden gemaakt van de hersenen van patiënten met deze oogziekten. Na een uitgebreide bewerking van deze beelden konden we de inhoud van delen van de hersenen van verschillende patiënten- en controlegroepen vergelijken. Hierbij hebben we specifiek gekeken naar de visuele banen. Dat is het deel van de hersenen waar de visuele informatie van het oog wordt doorgegeven naar het deel van de hersenen dat betrokken is bij het zien (de visuele cortex).

Publikasi 2021

Pseudo-colour with K-means Clustering Algorithm for Acute Ischemic Stroke Lesion Segmentation in Brain MRI

Abstrak

Segmentation of an acute ischemic stroke from a single modality of a greyscale magnetic resonance imaging (MRI) is an essential and challenging task. Recently, there are several numbers of related works on the automatic segmentation of infarct lesion from the input image and give a high accuracy in extraction of infarct lesion. Still, limited works have been reported in isolating the penumbra tissues and infarct core separately. The segmentation of the penumbra tissues is necessary because that region has the potential to recover. This paper presented an automated segmentation algorithm on diffusion-weighted magnetic resonance imaging (DW-MRI) image utilizing pseudo colour conversion and K-means clustering techniques. A greyscale image contains only intensity information and often misdiagnosed due to overlap intensity of an image. Colourization is the method of adding colours to greyscale images which allocate luminance or intensity for red, green, and blue channels. The greyscale image is converted to pseudo-colour is to intensify the visual perception and deliver more information. Then, the algorithm segments the region of interest (ROI) using K-means clustering. The result shows the potential of automated segmentation to differentiate between the healthy and lesion tissues with 90.08% in accuracy and 0.89 in dice coefficient. The development of an automated segmentation algorithm was successfully achieved by entirely depending on the computer with minimal interaction.

Publikasi 2021

Protecting from collateral damage

Abstrak

Organization (WHO) declared COVID-19 as a pandemic, just one month after the disease got its name (February 11th 2020). With a wide spectrum of signs and symptoms, surely COVID-19 is not just a bad case of cold. From being asymptomatic to being lethal, there is very much to comprehend from this novel viral infection. Here we will have a quick glance on what adverse effect the disease may have on the node of our sentience, the brain, and what we can do about it. The presence of change in mental status prompts brain imaging in COVID-19 infection. According to Egbert and colleagues, the prevailing neuroimaging features in the acute or subacute phase of the infection are diffuse leukoencephalopathy, leukoaraiosis, or rarefied white matter. This can be attributable to micro-haemorrhage, cerebrospinal fluid seepage from the ventricle, disruption of the blood-brain barrier, demyelination, or gliosis. Shortly later, Choi and Lee reported that the most common brain findings in the infection are infarct, haemorrhages, and inflammation or encephalopathy.

Publikasi 2019

FACTORS INFLUENCING SMOKING BEHAVIOR AND INTENSITY OF SANTRI IN ASRAMA PERGURUAN ISLAM (API) ISLAMIC BOARDING SCHOOL, TEGALREJO, MAGELANG, CENTRAL JAVA, INDONESIA

Abstrak

Introduction: Tabaco related death is estimated at 6 million people worldwide and it is portrayed to increase to 8 million in 2030. In ASEAN alone, there were approximately 121 million adult smokers in 2013, in which 50% of them were Indonesian. In Indonesia, it is illegal to sell cigarettes to people under 18 years old, but this regulation has weak field implementation and the number of under-age smokers is considerably high in Indonesia. Therefore, this study aimed to analyse the effects of knowledge and perception with smoking intention and behaviour among santris at Asrama Perguruan Islam (API) Islamic boarding school. Methods: A mix method study with sequential explanatory approach was conducted API Islamic boarding school in two phases namely qualitatively and quantitatively. 380 santris were enrolled in this study with interviewees for quantitative study was divided into three groups: santri who < 17 years old, santri who > 17 years old, and housekeepers. Results: The results showed that the knowledge significantly affected the smoking behaviour while had no influence toward smoking intention. On the other hand, no significant association was observed between perceptions with smoking intention while it significantly affected the smoking behaviour. Conclusion: It can be concluded that knowledge and perception were importance factors that influence smoking behaviour but had no effects toward smoking intention.

Publikasi 2021

The Effects of Local Food-Based Enteral Nutrition to Improve Nutritional Status of Post-Stroke Patients

Abstrak

Objective  We used local-based enteral formula for post-stroke patients to see its effects on the nutritional status. Materials and Methods  This is an experimental research with a pre- and post-test study design in post-stroke patients. Participants underwent clinical and laboratory examinations to assess their nutritional status before and after the enteral nutrition supplementation. The enteral formula preparation, containing arrowroot powder, cork fish, tempeh (fermented soybeans), nondairy creamer, and pumpkin, was performed in a nationally standardized Food Processing Technology Laboratory in Yogyakarta, Indonesia. The enteral formula was given twice a day for 3 consecutive weeks in addition to the patients’ daily meal. Statistical Analysis  Nutritional indices before and after enteral nutrition supplementation were analyzed using t-test . All statistical analyses were at 5% significance level. Results  Of the 22 post-stroke patients, we used the cutoff point of National Institutes of Health Stroke Scale ≥3 and Barthel Index <90 to represent dependency. Our findings showed significantly reduced mid-upper arm circumference and increased body mass index in independent post-stroke patients after the enteral nutrition supplementation. The tendency of increasing total cholesterol level should be carefully watched in dependent post-stroke patients. Conclusion  Local food-based enteral nutrition supplementation for 3 consecutive weeks in post-stroke patients may improve their nutritional status.

Publikasi 2020

Mental and Reproductive Health Disorders Due to Natural Hazzard (Study on Post Merapi Eruption to Women in Temporary Dwelling, Kuwang Cangkringan Sleman)

Abstrak

The objective of this study is to explore the condition of women as victims of Mt. Merapi eruption in Java Indonesia. The mental and reproductive health problems due to natural hazard can take up long time. Women and children are more prone to post-traumatic disorders. Findings from the data collected revealed that stressor from the disaster have positive impacts on depression, urinary tract infections (UTI) and menstrual disorders (reproductive health problems). The huge explosion in 2010 followed by the smaller eruptions which regularly exposed by the volcano made the residents could no longer live in their previous properties in the mountain feet. Their life has changed and adaptation is not always easy. In depth interviews revealed that surviving from huge loss is not easy. Lacking from non-farming skills made finding job is difficult. The numbers of people with mental disorders from Merapi eruption is quite significant and some remain in the psychiatric treatment. Government and community intervention are expected to help survival and minimize the negative impacts.

Penelitian 2019

MENTAL AND REPRODUCTIVE HEALTH DISORDERS DUE TO NATURAL HAZZARD (STUDY ON POST MERAPI ERUPTION TO WOMEN IN TEMPORARY DWELLING, KUWANG CANGKRINGAN SLEMAN)

Abstrak

The objective of this study is to explore the condition of women as victims of Mt. Merapi eruption in Java Indonesia. The mental and reproductive health problems due to natural hazard can take up long time. Women and children are more prone to post-traumatic disorders. Findings from the data collected revealed that stressor from the disaster have positive impacts on depression, urinary tract infections (UTI) and menstrual disorders (reproductive health problems). The huge explosion in 2010 followed by the smaller eruptions which regularly exposed by the volcano made the residents could no longer live in their previous properties in the mountain feet. Their life has changed and adaptation is not always easy. In depth interviews revealed that surviving from huge loss is not easy. Lacking from non-farming skills made finding job is difficult. The numbers of people with mental disorders from Merapi eruption is quite significant and some remain in the psychiatric treatment. Government and community intervention are expected to help survival and minimize the negative impacts.

Publikasi 2021

PENGETAHUAN, PERILAKU KEBERSIHAN DIRI DAN PENGOLAHAN JAJANAN SEHAT: SEBUAH STUDI PADA PEDAGANG ASONGAN DI NGAGLIK SLEMAN YOGYAKARTA

Abstrak

Pedagang asongan memiliki karakteristik beragam baik dari usia, jenis kelamin, tingkat pendidikan, pengetahuan dan perilaku. Perilaku kebersihan diri dan pengolahan jajanan yang baik menjadi jaminan keamanan untuk konsumen. Studi ini bertujuan untuk mengidentifikasi karakteristik, dan mencari hubungan antara tingkat pengetahuan, perilaku kebersihan diri dan pengolahan jajanan pedagang asongan. Studi dilaksanakan bulan maret 2020, dengan responden pedagang asongan di Kecamatan Ngaglik, Sleman, Yogyakarta. Studi ini merupakan studi cross sectional. Karakteristik responden diklasifikasikan berdasarkan usia, jenis kelamin, pendapatan, dan tingkat pendidikan. Variabel pengetahuan, perilaku kebersihan diri dan pengolahan jajanan para pedagang asongan. Responden dalam pengabdian masyarakat ini berjumlah 26 orang yang memenuhi kriterian inklusi dan eksklusi. Data diperoleh menggunakan kuesioner yang dilanjutkan dengan uji Fisher‟s exact test. Hasil studi ini menunjukkan pengetahuan tentang jajanan sehat berhubungan dengan tingkat pendidikan (p=0,46). Studi ini menunjukkan bahwa pedagang asongan disominasi oleh laki-laki (69,23%), tingkat pendidikan menengah (57,7%), pendapatan di bawah upah minimum kabupaten (73,07%). Tingkat pendidikan berhubungan dengan pengetahuan jajanan sehat (p=0,46), tetapi pengetahuan mengenai jajanan sehat, perilaku kebersihan diri dan pengolahan jajanan tidak saling berhubungan (p>0,05). Tingkat pengetahuan tentang jajanan sehat berhubungan dengan tingkat pendidikan, tetapi tingkat pengetahuan tidak berhungungan dengan perilaku kebersihan diri maupun pengolahan jajanan

Publikasi 2021

Effect of Dawood Fasting on the Increased Level of Antioxidant Enzymes

Abstrak

BACKGROUND: The incidence of degenerative diseases is increasing. The underlying mechanism for such disease includes rising oxidative stress without correspondingly adequate antioxidants. Intermittent fasting (IF) may stimulate mild oxidative stress with a corresponding increase in antioxidants. Dawood fasting (DF) as an alternative diet similar to IF is normally performed for <24 h (±14 h) with intermittent intervals of 1st-day fasting, 2nd-day ad libitum (AL) diet, 3rd-day fasting, and so on. AIM: The aim of this study to examine the effect of DF on the changes in superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (Cat) antioxidant enzymes in BALB/c strain mice. METHODS: A total of 15 BALB/c strain mice were randomly divided into three groups. The AL control (ALC) group was given a standard diet (AIN93) and AL drink every day. The high-fat diet control group was treated with a high-fat diet (24%) and daily AL drink. The DF group fasted on the 1st day (no food or drink) from 17:00 to 07:00, continued every other day, and given a standard feed (AIN93) and AL drink for 8 weeks. Examination of SOD levels in the liver as well as GPx and Cat levels in plasma was carried out using a spectrophotometer. The analysis was conducted using the one-way analysis of variance test followed by Tukey’s test (95% confidence level). RESULTS: The levels of SOD in ALC, DF, and HF groups were 52.86 ± 5.73%, 68.57 ± 3.7%, and 38.57 ± 4.3%, respectively (p = 0.00). The GPx levels were 43.06 ± 2.75 U/L, 55.54 ± 2.71 U/L, and 32.26 ± 2.14 U/L, respectively (p = 0.00), and the corresponding Cat levels were 5.82 ± 0.63 U/ml, 6.55 ± 0.64 U/ml, and 3.44 ± 0.64 U/ml (p = 0.00). CONCLUSION: The levels of SOD, GPx, and Cat antioxidant enzymes during DF were higher compared to an AL diet and a high-fat diet.